Volume: 56 Issue: 3
Year: 2025, Page: 444-449, Doi: https://doi.org/10.51966/jvas.2025.56.3.444-449
Received: Feb. 21, 2025 Accepted: May 17, 2025 Published: Sept. 30, 2025
This study aimed to evaluate the efficacy of progesterone nano cream (PNC) to induce oestrus and conception rate in crossbred dairy cows. Twenty four crossbred dairy cows were randomly divided into two groups on day 60 postpartum on the basis of presence or absence of corpus luteum viz. with CL and without CL, each group was further divided into treatment and control, with six animals in each subgroup. On Day 0 (day 60 postpartum) in treatment animals (group1- with CL and group 2- without CL) PNC was applied on depilated skin of forelimb below knee and secured with an adhesive and water resistant bandage. On day 6, Inj. Cloprostenol 500 μg (IM) was administered and on day 7, PNC bandage was removed. Control animals (group 3- with CL and 4- without CL) were observed over a period of 21 days from day 60 postpartum without any treatment. The oestrus induction response of group 1 and 2 was 100 and 83.33 per cent, respectively. The interval from PNC removal to induced oestrus was significantly (p < 0.01) lower in group 1 (54.60 ± 8.99 hours) than group 2 (118.80 ± 9.56 hours). Higher percentage of animals in control group displayed intense grade oestrus. The duration of oestrus in group 1 (56.00 7.16 hours) and group 2 (85.80 13.41 hours) was significantly (p < 0.05) longer than the control group 3 (30.33 ±1.45 hours) and group 4 (32 hours). The overall conception rate in group 1, 2, 3 and 4 were 83.33, 50, 66.67 and 50 per cent, respectively. The calving to first service interval was significantly (p < 0.05) lower in the treatment groups, and the calving to conception interval was also shorter compared to the control groups. It is concluded that PNC could effectively induce oestrus even in cows without ovarian rebound and thereby restoring ovarian cyclicity and shortening the intercalving interval.
Keywords: Progesterone nano cream, intercalving interval, oestrus induction, ovarian cyclicity
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© 2025 Rini et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Rini, M.M., Benjamin, E.D., Jayakumar, C., Becha, B.B., Abhilash, R.S., Mohan, K.M.S, Unnikrishnan, M.P. and Saifudeen, S.M. 2025. Efficacy of Progesterone nano cream (ProSync- NC) on oestrus induction and fertility outcomes in postpartum crossbred dairy cows. J. Vet. Anim. Sci. 56 (3):444-449