Volume: 41 Issue: 2
Year: 2010, Page: 54-57, Doi: https://doi.org/10.51966/jvas.2010.41.54-57
Received: Dec. 27, 2009 Accepted: May 4, 2010 Published: Dec. 31, 2010
Anoestrus bitches were treated with a sustained release preparation of leuprolide acetate @ 100 µg/kg body weight followed by gonadorelin @ 3 µg/kg body weight on the first day of induced oestrus. Bitches in natural proestrus were studied as controls. All the treated animals evinced proestrual bleeding by 4.67±0.21 days and oestrus by 12.67±0.49 days of treatment. The duration of proestrual bleeding was 6.67±0.56 days which was significantly shorter when compared to 8.67±0.42 days in controls. The intensity of proestrual bleeding and oestrus responses were pronounced in treated animals. There was no significant difference in the duration of oestrus, conception rate, gestation length and litter size between treated and control animals.
It is concluded that bitches in anoestrus could be induced to fertile oestrus reliably and rapidly using parenteral administration of a sustained release preparation of leuprolide acetate followed by gonadorelin, with a higher induction and conception rate with normal litter size.
Keywords: Anoestrus, Induction of oestrus, Leuprolide acetate