Volume: 48 Issue: 2
Year: 2017, Page: 90-92,
Received: July 2, 2016 Accepted: July 4, 2016 Published: Dec. 31, 2017
A study was conducted in 24 crossbred cows and endometrial sampling was performed by uterine cytobrush (UC) on 30, 40 and 50 days postpartum (DPP) to diagnose subclinical endometritis (SCE). Out of which 10 cows were diagnosed to be positive for SCE and were treated with E.colilipopolysaccharide (LPS). Polymorphonuclear (PMN) cells count byUC showed a significant reduction (P <0.001) inthe subsequent oestrus after treatment. All the animals showed significant improvement in tonicity of the uterus after treatment.The posttreatment pH(8.20 ± 0.11) was significantly lower (P <0.01) when compared to pre-treatment (7.40 ± 0.12).The overall conception rate of SCE cows was 60 per cent after treatment. So it is concluded that E.coli LPScould be used as an effective immunomodulator and as an alternative to antibiotic therapy.
Keywords: Subclinical endometritis, cytobrush, polymorphonuclear cells,lipopolysaccharide
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