Volume: 48 Issue: 2
Year: 2017, Page: 97-100,
Received: July 5, 2016 Accepted: July 5, 2016 Published: Dec. 31, 2017
Changes in haematological parameters in dogs with cystic endometrial hyperplasia-pyometra (CEH-Pyometra)was assessed. Haemoglobin (Hb), volume of packed red cells (VPRC), total erythrocyte count (TEC) and lymphocyte count were found to be decreased while the total leucocyte count (TLC) and neutrophil per cent was increased in dogs withCEH-Pyometra. Erythrocytic indices like mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) did not show any significant changes in these dogs and were in the normal range. Predominant leucocytosis(mean 25.56±2.24 ×103/mm3)with neutrophilia(mean84.83±1.22 %),lymphopenia (mean 12.33±0.95 %) and normocytic normochromic anaemiawere the most common findings in bitcheswith CEHPyometra.
Keywords: cystic endometrial hyperplasia, anaemia, bitch, leucocytosis, neutrophilia.
Bigliardi, E. and Pamigiani, E.2004. Ultrasonography and cystic hyperplasiapyometra complex in the bitch.Reprod. Dom. Anim. 39: 136–240
Dhabi D. M., Dhami A. J., Parikh P. V. and Patil D. B. 2009. Comparative evaluation of haematological parameters in healthy and pyometra affected bitches. Indian J. Anim. Reprod. 30 : 70-72.
Greene, C.E. 2006. In: Craig. E. Greene (ed.). Infectious diseases of the dog and cat (3rd. Ed.),W. B. Saunders Elsevier.p.1387.
Hagman, R., Kindahl, H., Fransson, B.A., Bergstro, M. A., Stro, M.,Holst, B. and Lagerstedt, A. S. 2006a. Differentiation between pyometra and cystic endometrial hyperplasia/mucometra in bitches by Prostaglandin F2a metabolite analysis. Theriogenology.66: 198–206.
Hagman, R. Kindahl, H. and Lagerstedt, A.S. 2006b. Pyometra in bitches induces elevated plasma endotoxin and prostaglandin F2α metabolite levels. Acta. Vet. Scand. 47: 55-68.
Hagman, R., Reezigt, B.J., Ledin,H.B. and Karlstam,E., 2009. Blood lactate levels in 31 female dogs with pyometra. Acta. Vet. Scand. 51: 2
Kashinath, S.K., Tiwari, R.S., Sumeet, G. and Osamah, M.K. 2009. Pyometra induced biochemical changes in bitches. Indian Vet.J.86: 853-855.
Memon, A.M., and Mickelsen, W.D. 1993. Diagnosis and Treatment of Closed– Cervix Pyometra in a Bitch. J. Am. Vet. Med. Assoc. 203: 509–512.
Murthy, V. C., Chithra, P.A., Krishnaswamy, A., Rao, S and Ramesh, P.T. 2013. Studies on certain clinical, haematological and biochemical parameters in pyometra of bitches. Indian J. Can. Pract. 5 . 125- 129
Nath K., Tiwari S. K. and Kalim O. 2009. Physiological and haematological changes in bitches with pyometra. Indian Vet. J. 86: 734-736.
Okano, S., Tagawa, M., Hara, Y., Ejima, H., Motoyoshi, S., Urakawa, N., Furakawa, K., Onda, M. and Ogawa,R. 1993. Changes in reticuloendothelial function in dogs with endotoxin-induced shock. J. Vet. Med. Sci. 55: 607-611.
Schepper J. D., Stock J. V. D. and Capiau E. (1987) Anaemia and leucocytosis in one hundred and twelve dogs with pyometra. J. Small Anim. Pract. 28 : 137-145.
The Merck’s Veterinary Manual. (2010). Merck & Co. Inc., Whitehouse Station, N.J., U.S.A. pp 2821- 2831
Verstegen, J., Dhaliwal, G. and Verstegen- Onclin, K.. 2008. Mucometra, cystic endometrial hyperplasia, and pyometra in the bitch: Advances in treatment and assessment of future reproductive success. Theriogenology.