Volume: 52 Issue: 4
Year: 2021, Page: 399-404, Doi: https://doi.org/10.51966/jvas.2021.52.4.399-404
Received: March 27, 2021 Accepted: Sept. 10, 2021 Published: Dec. 15, 2021
The study was aimed to investigate the hepato-protective effect of Moringa oleifera in Nile tilapia (Oreochromis niloticus) exposed to acetaminophen. Fishes exposed to sub-lethal concentration of acetaminophen for 96 hours, were fed on feed incorporated with moringa leaf, for 21 days. Histological studies of liver of fish fed with M. oleifera leaf incorporated feed , for 21 days after 96-hour acetaminophen exposure showed significant reparative changes when compared to the control. The experiment indicate that dietary supplementation of moringa leaf had hepatoprotective effect in Nile tilapia exposed to acetaminophen.
Keywords: Acetaminophen, Moringa oleifera, histopathology, hepatoprotection
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© 2021 Rema and Liji. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Rema, L.P. and Liji, C. B. 2021. Insights into the role of Moringa oleifera in ameliorating acetaminophen induced hepatotoxicity in Nile tilapia, Oreochromis niloticus. J. Vet. Anim. Sci. 52(4):399-404
DOI: https://doi.org/10.51966/jvas.2021.52.4.399-404