Volume: 53 Issue: 2
Year: 2022, Page: 262-268, Doi: https://doi.org/10.51966/jvas.2022.53.2.262-268
Received: Nov. 7, 2021 Accepted: Dec. 11, 2021 Published: June 30, 2022
Plants have been in use in medicine from time immemorial. Sesamum indicum, an ancient seed crop, has been widely used mainly for its oil. It is regarded as highly beneficial for its nutritive value and therapeutic effect. It is known to have anti-allergic, anti-inflammatory, anticancer, analgesic and many other pharmacological activities. In this study, seeds of S. indicum were subjected to aqueous extraction followed by evaluation for the presence of phytochemical constituents. The aqueous extract of seeds of S. indicum after phytochemical testing, was found to contain alkaloids, phenols, steroids, flavonoids, diterpenes, glycosides and tannins. Following this, silver nanoparticles were biosynthesised from the extract, where the phytochemicals acted as reducing and capping agents for the nanoparticles formed. The synthesised nanoparticles were characterised by using UV-visible spectroscopy, energy dispersive X-ray spectroscopy, field emission scanning electron microscopy and X-ray diffraction. The synthesis of nanoparticles from plant extract is gaining importance now-a-days owing to the effectual activity elicited by them when compared to activity of plant compounds alone
Keywords: Sesamum indicum, phytochemicals, silver nanoparticles
Aathira, K. K., Bibu, J. K., Dhanusha, G., Haima, J. S., Sujith, S., Shynu, M. and Nisha, A. R. 2021. Qualitative and quantitative analysis (GC-MS) of methanol extract of Crataeva nurvala stem bark. J. Vet. Anim. Sci. 52: 135-141.
Alfuraydi, A.A., Devanesan, S., Al-Ansari, M., AlSalhi, M.S. and Ranjitsingh, A.J. 2019. Eco-friendly green synthesis of silver nanoparticles from the sesame oil cake and its potential anticancer and antimicrobial activities. J. Photochem. Photobiol. 192: 83-89.
Anilakumar, K.R., Pal, A., Khanum, F. and Bawa, A.S. 2010. Nutritional, medicinal and industrial uses of sesame (Sesamum indicum L.) seeds-an overview. Agric. Conspec. Sci. 75: 159-168.
Azizi, S., Namvar, F., Mahdavi, M., Ahmad, M.B. and Mohamad, R. 2013. Biosynthesis of silver nanoparticles using brown marine macroalga, Sargassum muticum aqueous extract. Mater. 6: 5942-5950.
Basak, P., Majumder, R., Jasu, A., Paul, S. and Biswas, S. 2018. Potential Therapeutic Activity of Bio-Synthesized Silver Nanoparticles as Anticancer and Antimicrobial Agent. In IOP Conference Series: Materials Science and Engineering; September, 2018, p. 012020.
Basu, S., Maji, P. and Ganguly, J. 2016. Rapid green synthesis of silver nanoparticles by aqueous extract of seeds of Nyctanthes arbor-tristis. Appl. Nanosci. 6: 1-5.
Benakashani, F., Allafchian, A.R. and Jalali, S.A.H. 2016. Biosynthesis of silver nanoparticles using Capparis spinosa L. leaf extract and their antibacterial activity. Karbala Int. J. Mod. Sci. 2: 251-258.
Bhagat, M., Anand, R., Datt, R., Gupta, V. and Arya, S. 2019. Green synthesis of silver nanoparticles using aqueous extract of Rosa brunonii Lindl and their morphological, biological and photocatalytic characterizations. J. Inorg. Organomet. Polym. Mater. 29: 1039-1047.
Biswas, A., Dhar, P. and Ghosh, S. 2010. Antihyperlipidemic effect of sesame (Sesamum indicum L.) protein isolate in rats fed a normal and high cholesterol diet. J. Food Sci. 75: 274- 279.
Firdhouse, M.J. and Lalitha, P. 2015. Biosynthesis of silver nanoparticles and its applications. J. Nanotechnol. 2015: 1-15.
Ghani, N.A., Umran, M.A. and Shawkat, M.S. 2012. Cytotoxic activity of ethanol extract of Sesamum indicum seeds to cancer cell lines in vitro. Iraqi J. Med. Sci. 5: 28-33.
Ghojavand, S., Madani, M. and Karimi, J. 2020. Green synthesis, characterization and antifungal activity of silver nanoparticles using stems and flowers of felty germander. J. Inorg. Organomet. Polym. Mater. 30: 2987-2997.
Harborne, J.B. 1998. Phytochemical Methods: A guide to the modern techniques of plant analysis. (3rd Ed.) Chapman and Hall, London. 320p.
Hussain, S.A., Hameed, A., Ajmal, I., Nosheen, S., Suleria, H.A.R. and Song, Y. 2018. Effects of sesame seed extract as a natural antioxidant on the oxidative stability of sunflower oil. J. Food Sci. Technol. 55: 4099-4110.
Ibrahim, H.M. 2015. Green synthesis and characterization of silver nanoparticles using banana peel extract and their antimicrobial activity against representative microorganisms. J. Radiat. Res. Appl. Sci. 8: 265-275.
Keshari, A.K., Srivastava, R., Singh, P., Yadav, V.B. and Nath, G. 2020. Antioxidant and antibacterial activity of silver nanoparticles synthesized by Cestrum nocturnum. J. Ayurveda. Integr. Med. 11: 37-44.
Kuppusamy, P., Yusoff, M.M., Maniam, G.P. and Govindan, N. 2016. Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications–An updated report. Saudi Pharm. J. 24: 473-484.
Meena, R.K. and Chouhan, N. 2015. Biosynthesis of silver nanoparticles from plant (fenugreek seeds) reducing method and their optical properties. Res. J. Recent Sci. 4: 1-5.
Moldovan, B., David, L., Vulcu, A., Olenic, L., Perde-Schrepler, M., Fischer-Fodor, E., Baldea, I., Clichici, S. and Filip, G.A. 2017. In vitro and in vivo anti-inflammatory properties of green synthesized silver nanoparticles using Viburnum opulus L. fruits extract. Mater. Sci. Eng. C 79: 720-727.
Mushtaq, A., Hanif, M.A., Ayub, M.A., Bhatti, I.A. and Jilani, M.I. 2020. Sesame. In Medicinal Plants of South Asia. 601-615.
Nakano, D., Kwak, C.-J., Fujii, K., Ikemura, K., Satake, A., Ohkita, M., Takaoka, M., Ono, Y., Nakai, M. and Tomimori, N. 2006. Sesamin metabolites induce an endothelial nitric oxide-dependent vasorelaxation through their antioxidative property independent mechanisms: possible involvement of the metabolites in the antihypertensive effect of sesamin. J. Pharmacol. Exp. Ther. 318: 328- 335.
Narasimhan, R. and Mohan, A. 2012. Phytochemical screening of Sesamum indicum seed extract. Int. J. Pharm. Pharm. Sci. 1: 1298-1308.
Qais, F.A., Shafiq, A., Khan, H.M., Husain, F.M., Khan, R.A., Alenazi, B., Alsalme, A. and Ahmad, I. 2019. Antibacterial effect of silver nanoparticles synthesized using Murraya koenigii (L.) against multidrug-resistant pathogens. Bioinorg. Chem. Appl. 2019: 1-11.
Renjith, M.R.D. and Sankar, M. 2020. Scope of phytochemicals in the management of covid-19. Pharm. Res. 3: 26-29.
Saleem, T.M. 2011. Anti-microbial activity of sesame oil. Int. J. res. phytochem. pharmacol. 1: 21-23.
Shasmitha, R. 2015. Health benefits of Sesamum indicum: a short review. Asian J. Pharm. Clin. Res. 8: 1-3.
Subramanian, A.P., Jaganathan, S.K., Manikandan, A., Pandiaraj, K.N., Gomathi, N. and Supriyanto, E. 2016. Recent trends in nano-based drug delivery systems for efficient delivery of phytochemicals in chemotherapy. RSC Adv. 6: 48294-48314.
Sujitha, V., Murugan, K., Paulpandi, M., Panneerselvam, C., Suresh, U., Roni, M., Nicoletti, M., Higuchi, A., Madhiyazhagan, P., Subramaniam, J. and Dinesh, D. 2015. Green-synthesized silver nanoparticles as a novel control tool against dengue virus (DEN-2) and its primary vector Aedes aegypti. Parasitol. Res. 114: 3315-3325.
Suresh, G., Gunasekar, P.H., Kokila, D., Prabhu, D., Dinesh, D., Ravichandran, N., Ramesh, B., Koodalingam, A. and Siva, G.V. 2014. Green synthesis of silver nanoparticles using Delphinium denudatum root extract exhibits antibacterial and mosquito larvicidal activities. Spectrochim. Acta A. Mol. Biomol. Spectrosc. 127: 61-66.
Yadav, R.N.S. and Agarwala, M. 2011. Phytochemical analysis of some medicinal plants. J. Phytol. 3: 10-14.
© 2022 Keerthika et al. This is an open access article distributed under the terms of the Creative
Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits
unrestricted use, distribution, and reproduction in any medium, provided the original author and source are
credited
Keerthika, V., Nisha, A.R., Suresh, N. N., Preethy, J., Ramnath, V., Shankar, R. and Arya,
M. 2022. Phytochemical analysis and biosynthesis of silver nanoparticles from aqueous extract of
seeds of Sesamum indicum. J. Vet. Anim. Sci. 53(2): 262-268
DOI: https://doi.org/10.51966/jvas.2022.53.2.262-268